A man wakes up confused in a room with a laptop. Following a loud, wind-like sound the man loses the ability to speak which causes him to panic even further. We then see him run in-place and fall over. The camera then pans out, revealing two characters on the outside of a chamber that is holding the panicking man. It is then revealed that the man inside the chamber is a physics professor, and the two other characters had put him in a frictionless vacuum to see how he would work.
The joke here is that physics professors very commonly use a “frictionless vacuum” as the environment for problems and experiments given to their students. This is done to greatly simplify the work needed to solve the problem, as one can ignore the forces of friction and air resistance.
It’s also funny that they murdered a person.